Hi Charlie, thanks for posting and we're sorry to hear that your husband is experiencing rashes from Harvoni. Skin irritation and rashes are common with hepatitis C and can also come up during treatment, as unfortunately other users in this thread and your husband know first-hand. I wanted to link two articles we have on our website that may offer insights into managing the rashes. This article covers how skin is affected by hepatitis C and offers tips for management. A community member wrote this article on treating common skin issues too. I hope these can offer solutions to stop your husband's discomfort. Please let us know how he's doing as he finishes treatment. The hepatitisc.net community is here for you both. Best, Matt (HepatititsC.net, Team Member)