Hi . Many people experience anxiety when they take a new medication. So, know that you are not alone in your concerns. The cool thing is that, as soon as you took that first pill, you started on a path to better overall health. Hopefully, you'll kick this virus out of your body for good. You don't have to eat with Epclusa, but it's probably a good idea anyway. It can't hurt to cushion the impact on your stomach with a little food. I don't have experience with it, so I hope someone will jump in here with information about the potential onset of nausea. Keep in mind that the majority of people do not experience any nausea at all. You might be one of those lucky ones. Usually, if a pill cannot be crushed or cut, it says so on the label. Even so, I would check with a pharmacist before you take your next dose. Pharmacists are very knowledgeable about all things drug related, usually more so than doctors. If you are super concerned about cutting the pill and the anxiety interferes with your sleep, you might be able to reach someone at a 24-hour pharmacy by phone. According to the manufacturer's website, Epclusa only causes a slow heart rate when taken with amiodarone (Cordarone®, Nexterone®, Pacerone®). If you are not taking any of those medications, you should be fine. From what I have read in this community, most people are able to work throughout their treatment. One community member wrote about his experience with Epclusa treatment in this article: https://hepatitisc.net/spotlight/epclusa-experience. I thought it might bring you some comfort to read it. I hope this helps and that you feel a little better about the weeks ahead. Please know that we are here for you whenever you need support or a place to vent. Thinking of you and sending lots of positive vibes for a smooth treatment period and a full recovery. - Lori (Team Memeber)