The Sunshine Vitamin and Hep C
Last updated: June 2021
Most people have heard of Vitamin D, also commonly known as the “sunshine vitamin”. Vitamin D is a vitamin found in certain food. It can also be made by our skin in response to direct sunlight. Despite the abundance of this vitamin, people with hep C may be at a higher risk of Vitamin D deficiency. This leads to the question: Is it necessary for those with hep C to supplement with Vitamin D?
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What is Vitamin D?
Vitamin D is a fat soluble vitamin, which means that it is stored in body fat. Most people receive Vitamin D from the sun. In addition, there are a few food sources of Vitamin D, such as:
- Fatty fish, such as salmon
- Egg yolks
- Red Meat
As you may have noticed from the list, there are no plant sources of Vitamin D. In fact, most vegetarians and vegans -- who do not consume meat -- need to obtain their Vitamin D from the sun, fortified foods, or supplementation.
Vitamin D deficiency symptoms
Severe Vitamin D deficiency is unlikely to occur in the developed world; However, subclinical (or mild) deficiency is common. Because we store Vitamin D in the body, levels can decline in the winter. Levels also decline with age.1
Vitamin D deficiency can lead to various conditions, and an increased risk of:2
- Osteoporosis, a condition that affects the bones
- Falls and fractures
- Heart disease
Symptoms of Vitamin D deficiency are variable, and are generally non-specific. Most people are unaware of their deficiency until they undertake a blood test. Some symptoms of deficiency include:2
- Hair loss
- Joint pain
Besides hep C, other risk factors for developing Vitamin D deficiency include:3
- Use of certain medications, such as phenytoin for seizures
- Above average weight
- Dark skin
- Older age
- Less exposure to sunlight
- Issues with absorption, such as celiac disease
Vit D relationship's to hep C
Because one part of Vitamin D metabolism occurs in the liver, it has long been speculated that there is a link between hep C and Vitamin D deficiency. One study showed that low levels of Vitamin D is associated with an increased risk of developing advanced liver fibrosis, and lowered chance of achieving a cure from interferon treatment.4 Further studies have proposed that supplementing with Vitamin D can help improve response to treatment and protect against fibrosis.5
To supplement or not?
Vitamin D supplements are available over the counter and are quite affordable. If your doctor has not already checked your Vitamin D level, it may be a good idea to start there to determine whether supplementation would be beneficial. Even if you do not know your baseline Vitamin D level, there is very little overall risk of supplementation and most people can take a strength of 1000 IU/day safely.5
Do you supplement with Vitamin D? If so, what dose do you take? Share your experiences below!