Viral Load
The HCV/RNA test by PCR tells the doctor and patient how much virus is found in the blood of a hepatitis patient. Patients often refer to this test as either the viral load test or the PCR. This test is recommended when a person tests positive for the antibody to hepatitis C.
Antibodies indicate exposure
When no virus is found, even though the patient is antibody positive, it means he/she does not have hepatitis C. It means that at some point in their life, the person was exposed. With a positive antibody test and an undetected viral load result, either the patient was treated and is cured; or the patient fought the virus off without treatment, which happens about 20-25% of the time in the first 6 months after exposure; or the antibody test was a false positive or laboratory error. A false positive antibody test or lab error is quite uncommon.
The HCV/RNA test is the next step after a positive antibody test. The two reasons for a doctor to order the viral load test is to confirm a positive antibody test and secondly, after treatment, to know if the patient responded by clearing the virus from the blood. When a treated person has an undetected viral load twelve weeks after treatment ends with the direct-acting antivirals, he/she is considered cured. There is no reason at all to continue to check the viral load.
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